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Showing posts with label bentham. Show all posts
Showing posts with label bentham. Show all posts

Monday, 30 June 2014

Possibility Of Humans To Breathe Underwater In A Couple Of Decades


New revelations of researchers have opened the possibility that man, in a few decades time would be able to dive under water without any additional financing of oxygen flasks.

These are examinations of bioengineers, who discovered the path for men to uninhibitedly breathe under water, and clarified that later on, it could happen that a human DNA might be associated with the DNA of marine algae and plants.

For this research, a study was led an analysis that included a symbiosis of lizards and plants under water which produces oxygen. This blend was effective as these two were constantly joined with one another after the examination, which demonstrated that there may be a beneficial interaction between plants and vertebrates.


Interesting scientific news like these keeps the hope for the future bright. Obviously, future studies will concentrate more on the improvement of this process, so that one day it could be utilized on human beings for real. Similarly, human could utilize the abilities algae have, which would turn into a source of oxygen for people.

For a complete list, click on Bentham Science Publishers

Friday, 27 June 2014

Scientific news: Caffeine’s Prophylactic Effect towards Type 2 Diabetes


Type 2 diabetes represents 95% of aggregate diabetic people. According to reliable scientific news websites, its pervasiveness is expanding nowadays and researchers are working on revising the impact of caffeine on type 2 diabetes.

Diabetes type 2 is described by two conditions: insulin safety and dysfunctional β cell, prompting lower insulin secretion. It brings about expanded postprandial glucose levels which prompt hyperinsulinemia and hyperglycemic conditions.

There are different elements which represent this condition; like augmentation of free unsaturated fats, diminished glucose uptake, hereditary alteration, and expanded glucose creation (HGP).
Caffeine being a stimulatory element is found to decrease the dangers of type 2 diabetes. There are different factors included during this process:mobilization of calcium, inhibition of phosphodiesterase and antagonism of adenosine receptors. Likewise the studieshave demonstrated to have a reversal effect with prolonged usage of caffeine.


Caffeine lessensthe risk by releasing the catecholamine and glucose uptake, and acts as a prophylactic effect.

For a complete list, click on Bentham Science Publishers

Friday, 30 May 2014

Bio precursors and their Importance



A precursor is a compound that participates in the chemical reaction that produces another compound. In biochemistry, the term "precursor" is used more specifically to refer to a chemical compound preceding another in a metabolic pathway. The first ever bio precursor was made for Malaria.

Plasmodium falciparum is responsible of the most severe form of malaria, and new targets and novel chemotherapeutic scaffolds are needed to fight emerging multidrug-resistant strains of this parasite. Bis-alkylguanidines have been designed to mimic choline, resulting in the inhibition of plasmodial biosynthesis. 

Despite potent in vitro antiplasmodial and in vivo antimalarial activities, a major downside of these compounds for advance clinical growth is their short oral bioavailability. To explain this issue, several modulations were performed on bis-alkylguanidines. The introduction of N-disubstituents on the guanidine motif amended both in vitro and in vivo activities. On the other hand, in vivo pharmacological assessment in a mouse model showed that the N-hydroxylated derivatives constitute the first oral bioprecursors in bis-alkylguanidine sequences.

The article Design and Applications of Bioprecursors: A Retrometabolic Approach has given detailed information about bio precursor and their link for it to be a Retrometabolic approach. Also, the journal Current Drug Metabolism focuses on the roots of pharmacokinetics and pharmacodynamics.


 

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